Protein Details: Gap junction beta-6 protein

Protein ID

ICDB_Pro_0692

Protein Name

Gap junction beta-6 protein

Gene Name

Gjb6; Cxn-30

Organism

Mus musculus (Mouse)

Length

261 amino acids

AlphaFoldDB

AF-P70689-F1-model_v4.pdb

Function

Sequence

MDWGTLHTVIGGVNKHSTSIGKVWITVIFIFRVMILVVAAQEVWGDEQEDFVCNTLQPGCKNVCYDHFFPVSHIRLWALQLIFVSTPALLVAMHVAYYRHETARKFIRGEKRNEFKDLEDIKRQKVRIEGSLWWTYTSSIFFRIIFEAAFMYVFYFLYNGYHLPWVLKCGIDPCPNLVDCFISRPTEKTVFTVFMISASVICMLLNVAELCYLLLKLCFRRSKRTQAQRNHPNHALKESKQNEMNELISDSGQNAITSFPS

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Highly expressed in adult brain and skin. Less in uterus; lung and eye. Very low in testis and sciatic nerve. Very low in testis and sciatic nerve. Very low in testis and sciatic nerve. No expression before birth

DOI ID

10.1074/jbc.271.30.17903; 10.1101/gr.2596504; 10.1093/hmg/ddp490

RefSeq

NP_001010937.1; NP_001258592.1; XP_006518623.1; XP_006518624.1